Clinical Investigation and Translational Science

The Master of Science in Clinical Investigation and Translational Science (MSCI-TS) Degree Program  trains clinicians and health care professionals from diverse backgrounds and disciplines in the conduct of clinical investigations.  MSCI-TS program applicants must provide proof of either a degree in medicine, dentistry, graduate nursing, health professions, or evidence of concurrent enrollment in the Graduate School of Biomedical Sciences.  Post-doctoral (Ph.D.) applicants interested in human investigations are also welcome to apply.  Enrollees in the MSCI-TS Program must complete a mentored research project over two years while participating in a highly integrated set of didactic courses leading to the MSCI-TS degree.

Students will have the opportunity to become experts in the design and conduct of outstanding multidisciplinary patient-oriented research studies involving direct interaction with human subjects in culturally diverse settings.

Clinical Investigation and Translational Science Admissions Requirements

The MSCI-TS Program has an open application policy and will accept on-line applications for admission at any time.

However, GSBS deadlines (for submission of on-line applications and required documentation) for matriculation in a specific academic semester are listed below.

  • Fall Semester: April 1
  • Spring Semester: October 1
  • Applications for applicants intending to apply for or transfer an F-1 visa will only be accepted for consideration for matriculation in the Fall semester.

All transcripts from foreign institutions (including GPA) must be evaluated and submitted by an approved foreign credentialing evaluation agency.  Applicants should submit course by course transcript translations (including GPA) from the Educational Credential Evaluators, Inc. (ECE) or the World Education Services, Inc. (WES).

A minimum score of 300 (1,000 for scores prior to August 2011) score for the combined verbal and quantitative portions of the Graduate Record Examination (GRE) is required.

Applicants who have completed a graduate degree in a health-related discipline (M.D., D.D.S., R.N., D.V.M., M.S., or Ph.D.) will be exempted from the requirement to complete the GRE.

A minimum score of 560 on the paper version or 68 on the internet version of the Test of English as a Foreign Language (TOEFL) or 6.5 on the academic version of the International English Language Testing System (IELTS) for applicants from countries where English is not the native language.

Scores on TOEFL or IELS tests taken more than two years prior to the date of matriculation will not be accepted.

Letters of recommendation (three) attesting to the applicant's readiness for graduate level studies in clinical investigation.

  • Residents or fellows in an approved Health Science Center residency or fellowship program are required to submit a letter from the departmental Chairman with a statement indicating the availability and approval of release time for the completion of MSCI-TS educational and research activities.
  • Similarly, for Health Science Center staff, an authorized supervisor must provide a statement indicating the availability of release time for MSCI-TS educational and research activities.

A personal statement (1-2 pages) that includes a brief description of the applicant’s background, long term research and career goals, and an indication of the basis for application into the MSCI-TS Program including how this program fits into the applicant’s career objectives.

A current curriculum vitae is required.

Applicants requiring a student visa (requires full-time enrollment) are required to obtain a Supervising Professor, Supervising Committee, and submit a Research Proposal Packet on or before the application deadline for the Fall semester they are applying for.

Clinical Investigation and Translational Science Degree Requirements

Program Specific Policies for Student Manuscripts Required for Graduation

Students are required to submit a manuscript to the MSCI-TS COGS for consideration of their eligibility for candidacy for the MSCI-TS degree.

The manuscript must have already been submitted to a peer reviewed scientific journal – it may have been submitted, in press, or published during the interval that the student was enrolled in the MSCI-TS Program.

Manuscripts unrelated to the approved research project, such as case reports or book chapters, are not acceptable for completion of the manuscript requirement of the MSCI-TS degree.

Students are required to be a primary author (1st author) or share the position of primary author (2nd author).

In keeping with the responsible conduct of research, all manuscripts must comply with the specific requirements of the journal (e.g., responsibilities of the corresponding author). There will be no exception to this requirement.

Clinical Investigation and Translational Science Plan of Study

First Year
FallCredit Hours
TSCI 5070Responsible Conduct Of Patient-Oriented Clinical Research 2
TSCI 5071Patient-Oriented Clinical Research Methods-1 2
TSCI 5072Patient-Oriented Clinical Research Biostatistics-1 2
TSCI 6097Research 1-12
TSCI 5073Integrated Molecular Biology With Patient-Oriented Clinical Research 1
TSCI 5074Data Management, Quality Control And Regulatory Issues 2
TSCI 6060Patient-Oriented Clinical Research Methods-2 2
TSCI 6061Patient-Oriented Clinical Research Biostatistics-2 2
TSCI 6097Research 1-12
Second Year
TSCI 5075Scientific Communication 2
TSCI 5080Integrating Molecular Biology with Patient-Oriented Clinical Research Practicum 1
TSCI 6065Health Services Research 2
TSCI 6097Research 1-12
TSCI 6098Thesis 1 1-12
TSCI 6097Research 1 1-12
 Total Credit Hours: 23.0-78.0

No formal classes should be required during this semester. The research project should be completed and a manuscript prepared and submitted.

Clinical Investigation and Translational Science Objectives/Program Outcomes

  • Fundamental knowledge of and practice of ethics in research.
  • Competence in principles of research design/methods and data management/analysis.
  • Communicate research effectively in written and verbal communication.
  • Competence in research literature review and interpretation.
  • Conduct mentored research and submit results for publication.

Program Specific Policies for Student Research Projects

A Supervising Professor, Supervising Committee, and written research proposal must be approved by the MSCI-TS COGS before a student can enroll in TSCI 6097 Research (Mentored Research in Clinical Investigation).

Any changes to a student’s Supervising Professor, Supervising Committee, and written research proposal must be approved by the MSCI-TS COGS.

MSCI-TS students with an approved research project are required to prepare a semi-annual written report of progress for consideration by their Supervising Committee prior to the fall (August 31st) and spring (February 28th) semester deadlines.

Program Specific Policies for Laptop Computers

Students are required to have a laptop computer that can connect to and operate over a wireless network.

Software required:

  • Microsoft Office Suite (A personal copy of the latest version can be purchased at the Health Science Center bookstore at student pricing with a student ID)
  • Stata/IC (latest version required for TSCI 5072 Patient-Oriented Clinical Research Biostatistics-1)

Laptops with an Apple based Operating System must be able to also operate using a Windows based Operating System.